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Research highlight

Elucidating S1P-mediated signaling with biosensors
S1P binds to several G-protein-coupled receptors (GPCRs) activating a number of different signalling networks. This study explores these pathways by using a set of FRET-based biosensors for different RhoGTPases (Rac1, RhoA/B/C, Cdc42) as well as for heterotrimeric G-proteins in a series of live-cell imaging experiments in primary human endothelial cells. read more...

Bright red fluorescent protein created
After years of trying, biologists have succeeded in creating an extremely bright red fluorescent protein in the lab. This is good news for researchers, including cancer and stem cell researchers, who use fluorescent proteins to track essential cellular processes.

The researchers at the University of Amsterdam & Institut de Biologie structurale and the European Synchrotron in Grenoble describe their approach in the latest edition of the journal Nature Methods. Nature Methods.

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Molecular Cytology

The section of Molecular Cytology is located at the Swammerdam Institute for Life Sciences, part of the Faculty of Science at the University of Amsterdam. The central research theme is 'Self-organisation and signalling in living cells'. To study this we make use of the wide range of fluorescence microscopes of the van Leeuwenhoek Centre for Advanced Microscopy that is embedded in the section.

For more info about Molecular Cytology:
Prof. dr. Dorus Gadella
room C2.266
Sciencepark 904
The Netherlands
Tel: -31-(0)20-525 6259

Website: Marten Postma